| Episode # |
Original
Air Date |
Guests |
| |
| Season 1 |
| |
| 1. | 1-1 | 26 Jun 16 | Debra Messing, J.B. Smoove, Michael Ian Black, Rosie O'Donnell, Sutton Foster, Tituss Burgess |
| 2. | 1-2 | 03 Jul 16 | Adam Goldberg, Ana Gasteyer, Horatio Sanz, Rosie O'Donnell, Sherri Shepherd, Tituss Burgess |
| 3. | 1-3 | 10 Jul 16 | Ana Gasteyer, Bobby Moynihan, Maggie Q, Pete Wentz, Rosie O'Donnell, Tituss Burgess |
| 4. | 1-4 | 17 Jul 16 | Cheryl Hines, Ike Barinholtz, Jack McBrayer, Josh Charles, Leah Remini, Leslie Jones |
| 5. | 1-5 | 24 Jul 16 | David Alan Grier, Ellie Kemper, Jack McBrayer, Jason Alexander, Niecy Nash, Sheryl Crow |
| 6. | 1-6 | 31 Jul 16 | Alexandra Wentworth, Kal Penn, Jack McBrayer, Niecy Nash, Mario Cantone, Cheryl Hines |
| 7. | 1-7 | 14 Aug 16 | Ellie Kemper, David Alan Grier, Jack McBrayer, Jerry O'Connell, Natasha Lyonne, Niecy Nash |
| 8. | 1-8 | 21 Aug 16 | Rosie O'Donnell, Sherri Shepherd, Horatio Sanz, Isaac Mizrahi, Edie Falco, D.L. Hughley |
| 9. | 1-9 | 28 Aug 16 | Ellie Kemper, David Alan Grier, Jack McBrayer, Joshua Malina, Sherri Shepherd, Sheryl Crow |
| 10. | 1-10 | 19 Sep 16 | Jack McBrayer, J.B. Smoove, Kristin Chenoweth, Leah Remini, Randall Park, Sarah Palin |
| |
| Season 2 |
| |
| 11. | 2-1 | 04 Jan 17 | Jason Alexander, Cheryl Hines, Ice T, Ellie Kemper, Wayne Brady, Caroline Rhea |
| 12. | 2-2 | 11 Jan 17 | Amy Sedaris, Chris D'Elia, Constance Zimmer, Jane Krakowski, Rick Fox, Tituss Burgess |
| 13. | 2-3 | 18 Jan 17 | Andy Richter, Bellamy Young, Caroline Rhea, Judy Greer, Neil deGrasse Tyson, Skylar Astin |
| 14. | 2-4 | 08 Feb 17 | Caroline Rhea, Chris D'Elia, Judah Friedlander, Judy Greer, Mekhi Phifer, Vivica A. Fox. |
| 15. | 2-5 | 15 Feb 17 | Adam Carolla, Ana Gasteyer, Cheryl Hines, Jenna Fischer, Justin Long, Kenan Thompson |
| 16. | 2-6 | 22 Feb 17 | Casey Wilson, Lamorne Morris, Leah Remini, Mario Cantone, Niecy Nash, Scott Wolf |
| 17. | 2-7 | 02 Apr 17 | Tituss Burgess, Jane Krakowski, Matthew Morrison, Busy Philipps, Taye Diggs, Valerie Bertinelli |
| 18. | 2-8 | 09 Apr 17 | Adam Carolla, Jenna Fischer, Tyson Beckford, Caroline Rhea, Jay Pharoah, Ana Gasteyer |
| 19. | 2-9 | 16 Apr 17 | Horatio Sanz, Niecy Nash, Mario Cantone, Casey Wilson, Lamorne Morris, Martha Stewart |
| 20. | 2-10 | 23 Apr 17 | Jason Alexander, Cheryl Hines, Joe Lo Truglio, Ellie Kemper, Wayne Brady, Caroline Rhea |
| 21. | 2-11 | 30 Apr 17 | Adam Carolla, Ana Gasteyer, Chris Colfer, Christie Brinkley, Jay Pharoah, Wendie Malick |
| 22. | 2-12 | 14 May 17 | Tituss Burgess, Jane Krakowski, Sasheer Zamata, Darrell Hammond, Rick Fox, Constance Zimmer |
| |
| Season 3 |
| |
| 23. | 3-1 | 03 Jan 18 | Joel McHale, Niecy Nash, Mark Duplass, Caroline Rhea, Jason Ritter, Constance Zimmer |
| 24. | 3-2 | 10 Jan 18 | Jack McBrayer, NeNe Leakes, Max Greenfield, Christina Ricci, Kenny G, Jane Krakowski |
| 25. | 3-3 | 17 Jan 18 | Adam Pally, Cheryl Hines, Ron Funches, Caroline Rhea, Mario Cantone, Ana Gasteyer |
| 26. | 3-4 | 24 Jan 18 | Jack McBrayer, Ellie Kemper, Anthony Anderson, Yvette Nicole Brown, James Van Der Beek, Anna Camp |
| 27. | 3-5 | 31 Jan 18 | Jack McBrayer, Jane Krakowski, Rob Huebel, Ana Gasteyer, Jason Biggs, Tichina Arnold |
| 28. | 3-6 | 07 Feb 18 | Lynda Carter, Sam Richardson, Cheryl Hines, Colton Haynes, Caroline Rhea, Taye Diggs |
| 29. | 3-7 | 14 Feb 18 | Colin Quinn, Judy Greer, Judah Friedlander, Caroline Rhea, Orlando Jones, Abby Elliott |
| 30. | 3-8 | 21 Feb 18 | Horatio Sanz, Amy Sedaris, Tim Meadows, Niecy Nash, RuPaul, Leah Remini |
| 31. | 3-9 | 21 Jun 18 | Kenan Thompson, Niecy Nash, Thomas Lennon, Caroline Rhea, Mark Duplass, Constance Zimmer |
| 32. | 3-10 | 28 Jun 18 | Jack McBrayer, Jenifer Lewis, James Van Der Beek, Ellie Kemper, Anthony Anderson, Kate Flannery |
| 33. | 3-11 | 05 Jul 18 | Joel McHale, Constance Zimmer, David Arquette, Caroline Rhea, Michael Ealy, Laverne Cox |
| 34. | 3-12 | 12 Jul 18 | Jack McBrayer, Ellie Kemper, John Early, Yvette Nicole Brown, Donald Faison, Amy Sedaris |
| 35. | 3-13 | 19 Jul 18 | Mario Cantone, Cheryl Hines, Adam Pally, Caroline Rhea, Neil deGrasse Tyson, and Niecy Nash |
| 36. | 3-14 | 26 Jul 18 | Jack McBrayer, Christina Ricci, Ice-T, Jane Krakowski, Tituss Burgess, Nikki Glaser |
| 37. | 3-15 | 09 Aug 18 | Jason Alexander, Sheryl Underwood, Gabriel Iglesias, Constance Zimmer, Bubba Watson, Anjelah Johnson |
| 38. | 3-16 | 16 Aug 18 | Kenan Thompson, Thomas Lennon, Sherri Shepherd, Horatio Sanz, Gillian Jacobs |
| 39. | 3-17 | 06 Sep 18 | Mario Cantone, Sandra Bernhard, Oliver Hudson, Caroline Rhea, Adam Rodriguez, Eva Marcille |
| 40. | 3-18 | 13 Sep 18 | Pamela Anderson, Ali Wentworth, Sugar Ray Leonard, Tisha Campbell-Martin, Adam Carolla, Mark Duplass |
| |
| Season 4 |
| |
| 41. | 4-1 | 09 Jan 19 | Kenan Thompson, Ellie Kemper, Tyler Hoechlin, Sherri Shepherd, Horatio Sanz, Jillian Bell |
| 42. | 4-2 | 16 Jan 19 | Joel McHale, Jane Krakowski, Finesse Mitchell, Caroline Rhea, Jason Biggs, La Toya Jackson |
| 43. | 4-3 | 23 Jan 19 | Adam Carolla, Morena Baccarin, Johnny Weir, Cheryl Hines, Rick Fox, Pamela Anderson |
| 44. | 4-4 | 30 Jan 19 | Chris Parnell, Whitney Cummings, Kevin Smith, Jane Krakowski, Ron Funches, Caitlyn Jenner |
| 45. | 4-5 | 13 Feb 19 | Jason Alexander, Niecy Nash, Judah Friedlander, Constance Zimmer, Michael Che, Erika Christensen |
| 46. | 4-6 | 20 Feb 19 | Mario Cantone, Raven-Symoné, Oliver Hudson, Caroline Rhea, Finesse Mitchell, Julie Klausner |
| 47. | 4-7 | 12 Jun 19 | Jason Alexander, Sheryl Underwood, Gabriel Iglesias, Constance Zimmer, Michael Che, Bridget Everett |
| 48. | 4-8 | 19 Jun 19 | Chris Parnell, Whitney Cummings, Tony Rock, Jane Krakowski, Rob Riggle, Sarah Chalke |
| 49. | 4-9 | 26 Jun 19 | Joel McHale, Rachael Ray, Jason Biggs, Caroline Rhea, Donald Faison, Vanessa Williams. |
| 50. | 4-10 | 17 Jul 19 | Mario Cantone, Raven Symoné, Hasan Minhaj, Caroline Rhea, Wayne Newton, Sandra Bernhard |
| 51. | 4-11 | 24 Jul 19 | Chris Parnell, Kym Whitley, Rob Riggle, Caitlyn Jenner, Jay Pharoah, Sarah Chalke. |
| 52. | 4-12 | 31 Jul 19 | Horatio Sanz, Sherri Shepherd, Thomas Lennon, Ellie Kemper, Kenan Thompson, Kyle Richards |
| 53. | 4-13 | 07 Aug 19 | Michael Che, Kirstie Alley, Chris D'Elia, Sherri Shepherd, Mark Duplass, Brooklyn Decker |
| 54. | 4-14 | 14 Aug 19 | Code Blue |
| |
| Season 5 |
| |
| 55. | 5-1 | 31 May 20 | Shooting Blanks (Mario Cantone, Adam Rodriguez, Angie Harmon, Jennifer Esposito, Melissa Fumero, Michael Chiklis) |
| 56. | 5-2 | 07 Jun 20 | Sam Richardson, Jane Krakowski, Ben Schwartz, Caroline Rhea, James Van Der Beek, Vivica A Fox |
| 57. | 5-3 | 14 Jun 20 | Joel McHale, Amy Sedaris, Kevin Smith, Raven-Symoné, Ne-Yo, Malin Akerman |
| 58. | 5-4 | 28 Jun 20 | Thomas Lennon, Mary McCormack, Rick Fox, Caroline Rhea, Bob Saget, Padma Lakshmi |
| 59. | 5-5 | 12 Jul 20 | Adam Carolla, Cheryl Hines, Nick Swisher, Ali Wentworth, Mark Duplass, Loni Love |
| 60. | 5-6 | 24 Sep 20 | 58th Episode Celebration- Jerry Ferrara, Constance Zimmer, Chris Sullivan, Caroline Rhea, Ross Matthews, Dascha Polanco |
| 61. | 5-7 | 01 Oct 20 | James Van Der Beek, Cheryl Hines, Thomas Lennon, Sherri Shepherd, Dr. Oz, Laura Benanti |
| 62. | 5-8 | 08 Oct 20 | Joel McHale, Amanda Seales, Ron Funches, Ana Gasteyer, Rob Huebel, Nikki Glaser |
| 63. | 5-9 | 29 Oct 20 | Joel McHale, Jane Krakowski, Jermaine Fowler, Caroline Rhea, Skylar Astin, Retta |
| 64. | 5-10 | 21 Jul 21 | Match Gala - Mario Cantone, Vivica A Fox, Antonio Brown, Hilaria Baldwin, Fred Armisen, Christie Brinkley |
| 65. | 5-11 | 28 Jul 21 | Horatio Sanz, Marilu Henner, Michael Colter, Ali Wentworth, Justin Long, Drea de Matteo |
| |
| Season 6 |
| |
| 66. | 6-1 | 23 Jul 25 | Kevin Nealon, Selena Gomez, BD Wong, Anthony Anderson, Cara Delevingne, Ziwe |
| 67. | 6-2 | 30 Jul 25 | Caroline Rhea, Jay Pharoah, Ana Gasteyer, Phoebe Robinson, Randall Park, Constance Zimmer |
| 68. | 6-3 | 06 Aug 25 | Ego Nwodim, Jackie Tohn, Triumph the Insult Comic Dog, Andrea Martin, Thomas Lennon, Pete Holmes |
| 69. | 6-4 | 13 Aug 25 | Da'Vine Joy Randolph, Caroline Rhea, Constance Zimmer, Adam Pally, Beanie Feldstein, Joel Kim Booster |
| 70. | 6-5 | 20 Aug 25 | Joel McHale, Amy Sedaris, Lamorne Morris, Kevin Nealon, Ziwe, Annie Murphy |
| 71. | 6-6 | 27 Aug 25 | Thomas Lennon, Andrea Martin, Tituss Burgess, Ego Nwodim, Pete Holmes, Von Miller |
| 72. | 6-7 | 03 Sep 25 | Anthony Anderson, Annie Murphy, Joel McHale, Selena Gomez, Cara Delevingne, Thomas Lennon |
| 73. | 6-8 | 10 Sep 25 | Adam Pally, Randall Park, Kal Penn, Ana Gasteyer, Da'Vine Joy Randolph, Beanie Feldstein |
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