| Episode # |
Original
Air Date |
Guests |
| |
| Season 2020 |
| |
| 1. | 2020-1 | 14 Sep 20 | September 14, 2020 - Adam Sandler |
| 2. | 2020-2 | 15 Sep 20 | September 15, 2020 - Reese Witherspoon |
| 3. | 2020-3 | 16 Sep 20 | September 16, 2020 - Jane Fonda |
| 4. | 2020-4 | 17 Sep 20 | September 17, 2020 - Jonah Larson |
| 5. | 2020-5 | 18 Sep 20 | September 18, 2020 - Billy Porter |
| 6. | 2020-6 | 21 Sep 20 | September 21, 2020 - Paris Hilton |
| 7. | 2020-7 | 22 Sep 20 | September 22, 2020 - Gwyneth Paltrow |
| 8. | 2020-8 | 23 Sep 20 | September 23, 2020 - Stephen Colbert |
| 9. | 2020-9 | 24 Sep 20 | September 24, 2020 - Rosario Dawson |
| 10. | 2020-10 | 25 Sep 20 | September 25, 2020 - Tom Green |
| 11. | 2020-11 | 28 Sep 20 | September 28, 2020 - Julianne Moore |
| 12. | 2020-12 | 29 Sep 20 | September 29, 2020 - Savannah Guthrie |
| 13. | 2020-13 | 30 Sep 20 | September 20, 2020 - Nicole Richie |
| 14. | 2020-14 | 01 Oct 20 | October 1, 2020 - Andrew Rannells |
| 15. | 2020-15 | 02 Oct 20 | October 2, 2020 - Jason Sudeikis |
| 16. | 2020-16 | 05 Oct 20 | October 5, 2020 - Phoebe Robinson |
| 17. | 2020-17 | 06 Oct 20 | October 6, 2020 - Jane Lynch |
| 18. | 2020-18 | 07 Oct 20 | October 7, 2020 - Jonathan Van Ness |
| 19. | 2020-19 | 08 Oct 20 | October 8, 2020 - Kathie Lee Gifford |
| 20. | 2020-20 | 09 Oct 20 | October 9, 2020 - James Corden |
| 21. | 2020-21 | 12 Oct 20 | October 12, 2020 - Jessica Alba |
| 22. | 2020-22 | 13 Oct 20 | October 13, 2020 - Gloria Estefan |
| 23. | 2020-23 | 14 Oct 20 | October 14, 2020 - Sharon Stone |
| 24. | 2020-24 | 15 Oct 20 | October 15, 2020 - Henry Winkler |
| 25. | 2020-25 | 16 Oct 20 | October 16, 2020 - Hoda Kotb |
| 26. | 2020-26 | 19 Oct 20 | October 19, 2020 - Rachael Ray |
| 27. | 2020-27 | 20 Oct 20 | October 20, 2020 - June Diane Raphael |
| 28. | 2020-28 | 21 Oct 20 | October 21, 2020 - Glennon Doyle |
| 29. | 2020-29 | 22 Oct 20 | October 22, 2020 - Karamo Brown |
| 30. | 2020-30 | 23 Oct 20 | October 23, 2020 - Seth MacFarlane |
| 31. | 2020-31 | 26 Oct 20 | October 26, 2020 - Adam Sandler |
| 32. | 2020-32 | 27 Oct 20 | October 27, 2020 - Stanley Tucci |
| 33. | 2020-33 | 28 Oct 20 | October 28, 2020 - Dr. Phil |
| 34. | 2020-34 | 29 Oct 20 | October 29, 2020 - Anne Hathaway |
| 35. | 2020-35 | 30 Oct 20 | October 30, 2020 - Ashley Park |
| 36. | 2020-36 | 02 Nov 20 | November 2, 2020 - Chelsea Handler |
| 37. | 2020-37 | 03 Nov 20 | November 3, 2020 - Jessica Capshaw |
| 38. | 2020-38 | 04 Nov 20 | November 4, 2020 - David Dobrik |
| 39. | 2020-39 | 05 Nov 20 | November 5, 2020 - Gabriel Iglesias |
| 40. | 2020-40 | 06 Nov 20 | November 6, 2020 - Winnie Harlow |
| 41. | 2020-41 | 09 Nov 20 | November 9, 2020 - Zooey Deschanel |
| 42. | 2020-42 | 10 Nov 20 | November 10, 2020 - Rebel Wilson |
| 43. | 2020-43 | 11 Nov 20 | November 11, 2020 - Milo Ventimiglia |
| 44. | 2020-44 | 12 Nov 20 | November 12, 2020 - Chris O'Donnell |
| 45. | 2020-45 | 13 Nov 20 | November 13, 2020 - Emma Roberts |
| 46. | 2020-46 | 16 Nov 20 | November 16, 2020 - Iman |
| 47. | 2020-47 | 17 Nov 20 | November 17, 2020 - Michael Strahan |
| 48. | 2020-48 | 18 Nov 20 | November 17, 2020 - Megan Rapinoe |
| 49. | 2020-49 | 19 Nov 20 | November 16, 2020 - Liza Koshy |
| 50. | 2020-50 | 20 Nov 20 | November 16, 2020 - Miranda Kerr |
| 51. | 2020-51 | 23 Nov 20 | November 23, 2020 - Annaleigh Ashford |
| 52. | 2020-52 | 24 Nov 20 | November 24, 2020 - Kay and Camila McConaughey |
| 53. | 2020-53 | 25 Nov 20 | November 25, 2020 - Kelly Rowland |
| 54. | 2020-54 | 30 Nov 20 | November 30, 2020 - Hunter McGrady |
| 55. | 2020-55 | 01 Dec 20 | December 1, 2020 - Gordon Ramsay |
| 56. | 2020-56 | 02 Dec 20 | December 2, 2020 - Jenny Slate |
| 57. | 2020-57 | 03 Dec 20 | December 3, 2020 - Jennifer Garner |
| 58. | 2020-58 | 04 Dec 20 | December 4, 2020 - Martha Stewart |
| 59. | 2020-59 | 07 Dec 20 | December 7, 2020 - Jimmy Fallon |
| 60. | 2020-60 | 08 Dec 20 | December 8, 2020 - Ken Jeong |
| 61. | 2020-61 | 09 Dec 20 | December 9, 2020 - Neil Patrick Harris |
| 62. | 2020-62 | 10 Dec 20 | December 10, 2020 - Ellie Kemper |
| 63. | 2020-63 | 11 Dec 20 | December 11, 2020 - Kristen Bell |
| 64. | 2020-64 | 14 Dec 20 | December 14, 2020 - Elaine Welteroth |
| 65. | 2020-65 | 15 Dec 20 | December 15, 2020 - Zosia Mamet |
| 66. | 2020-66 | 16 Dec 20 | December 16, 2020 - Joe Manganiello |
| 67. | 2020-67 | 17 Dec 20 | December 17, 2020 - Natalie Portman |
| 68. | 2020-68 | 21 Dec 20 | December 21, 2020 - Kate Mara |
| |
| Season 2021 |
| |
| 69. | 2021-1 | 04 Jan 21 | January 4, 2021 - Nikki Glaser |
| 70. | 2021-2 | 05 Jan 21 | January 5, 2021 - Judge Marilyn Milian |
| 71. | 2021-3 | 06 Jan 21 | January 6, 2021 - Charlize Theron |
| 72. | 2021-4 | 07 Jan 21 | January 7, 2021 - Danny Seo |
| 73. | 2021-5 | 08 Jan 21 | January 8, 2021 - Karamo Brown |
| 74. | 2021-6 | 11 Jan 21 | January 11, 2021 - Craig Ferguson |
| 75. | 2021-7 | 12 Jan 21 | January 12, 2021 - Carrie Underwood |
| 76. | 2021-8 | 13 Jan 21 | January 13, 2021 - Jane Krakowski |
| 77. | 2021-9 | 14 Jan 21 | January 14, 2021 - Meagan Good |
| 78. | 2021-10 | 15 Jan 21 | January 15, 2021 - Ralph Macchio |
| 79. | 2021-11 | 18 Jan 21 | January 18, 2021 - Danny Seo |
| 80. | 2021-12 | 19 Jan 21 | January 19, 2021 - Cole Sprouse |
| 81. | 2021-13 | 20 Jan 21 | January 20, 2021 - Karamo Brown |
| 82. | 2021-14 | 21 Jan 21 | January 21, 2021 - Kat Graham |
| 83. | 2021-15 | 22 Jan 21 | January 22, 2021 - Taye Diggs |
| 84. | 2021-16 | 25 Jan 21 | January 15, 2021 - Dakota Johnson |
| 85. | 2021-17 | 26 Jan 21 | January 26, 2021 - Matthew McConaughey |
| 86. | 2021-18 | 27 Jan 21 | January 27, 2021 - Drew Carey |
| 87. | 2021-19 | 28 Jan 21 | January 28, 2021 - Wayne Brady |
| 88. | 2021-20 | 29 Jan 21 | January 29, 2021 - Leah Remini. |
| 89. | 2021-21 | 01 Feb 21 | February 1, 2021 - Jameela Jamil |
| 90. | 2021-22 | 02 Feb 21 | February 2, 2021 - Lilly Singh |
| 91. | 2021-23 | 03 Feb 21 | February 3, 2021 - The Talk |
| 92. | 2021-24 | 04 Feb 21 | February 4, 2021 - Josh Lucas |
| 93. | 2021-25 | 05 Feb 21 | February 5, 2021 - Rachael Ray |
| 94. | 2021-26 | 08 Feb 21 | February 8, 2021 - Patti LaBelle |
| 95. | 2021-27 | 09 Feb 21 | February 9, 2021 - Katherine Heigl |
| 96. | 2021-28 | 10 Feb 21 | February 10, 2021 - Lionel Richie |
| 97. | 2021-29 | 11 Feb 21 | February `11, 2021 - Giada De Laurentiis |
| 98. | 2021-30 | 12 Feb 21 | February 12, 2021 - Lana Condor |
| 99. | 2021-31 | 16 Feb 21 | February 16, 2021 - Ricki Lake |
| 100. | 2021-32 | 17 Feb 21 | February 17, 2021 - Jennifer Love Hewitt |
| 101. | 2021-33 | 18 Feb 21 | February 18, 2021 - Kat Dennings |
| 102. | 2021-34 | 19 Feb 21 | February 19, 2021 - Jason Biggs |
| 103. | 2021-35 | 22 Feb 21 | February 22, 2021 - David Letterman |
| 104. | 2021-36 | 23 Feb 21 | February 23, 2021 - Kristen Wiig |
| 105. | 2021-37 | 24 Feb 21 | February 24, 2021 - Ben Platt |
| 106. | 2021-38 | 25 Feb 21 | February 25, 2021 - Andra Day |
| 107. | 2021-39 | 26 Feb 21 | February 26, 2021 - Chloe Grace Moretz |
| 108. | 2021-40 | 01 Mar 21 | March 1, 2021 - Leslie Mann |
| 109. | 2021-41 | 02 Mar 21 | March 2, 2021 - Dr. Oz |
| 110. | 2021-42 | 03 Mar 21 | March 3, 2021 - Stephen King |
| 111. | 2021-43 | 04 Mar 21 | March 4, 2021 - Kelly Marie Tran |
| 112. | 2021-44 | 05 Mar 21 | March 5, 2021 - Zach Braff |
| 113. | 2021-45 | 08 Mar 21 | March 8 - Diane von Furstenberg |
| 114. | 2021-46 | 09 Mar 21 | March 9 - Oliver Hudson |
| 115. | 2021-47 | 10 Mar 21 | March 10 - Ike Barinholtz |
| 116. | 2021-48 | 11 Mar 21 | March 11 - Phil Donahue |
| 117. | 2021-49 | 12 Mar 21 | March 12 - Eddie Murphy |
| 118. | 2021-50 | 15 Mar 21 | March 15, 2021 - Idina Menzel |
| 119. | 2021-51 | 16 Mar 21 | March 16, 2021 - Anthony Anderson and Doris Bowman |
| 120. | 2021-52 | 17 Mar 21 | March 17, 2021 - Lamorne Morris |
| 121. | 2021-53 | 18 Mar 21 | March 18, 2021 - Mayim Bialik |
| 122. | 2021-54 | 19 Mar 21 | March 19, 2021 - Nick Offerman |
| 123. | 2021-55 | 22 Mar 21 | March 22, 2021 - Joel McHale |
| 124. | 2021-56 | 23 Mar 21 | March 23, 2021 - Alyson Hannigan |
| 125. | 2021-57 | 24 Mar 21 | March 24, 2021 - Sara Gilbert |
| 126. | 2021-58 | 25 Mar 21 | March 25, 2021 - Khloe Kardashian |
| 127. | 2021-59 | 26 Mar 21 | March 26, 2021 - Edgar Ramirez |
| 128. | 2021-60 | 29 Mar 21 | March 29, 2021 - Giada De Laurentiis |
| 129. | 2021-61 | 30 Mar 21 | March 30, 2021 - Jesse Tyler Ferguson |
| 130. | 2021-62 | 31 Mar 21 | March 31, 2021 - Kenan Thompson |
| 131. | 2021-63 | 01 Apr 21 | April 1, 2021 - Seth Meyers |
| 132. | 2021-64 | 02 Apr 21 | April 2, 2021 - Chris Jackson |
| 133. | 2021-65 | 05 Apr 21 | April 5, 2021 - Brené Brown |
| 134. | 2021-66 | 06 Apr 21 | April 6, 2021 - Allison Janney |
| 135. | 2021-67 | 07 Apr 21 | April 7, 2021 - Lee Daniels |
| 136. | 2021-68 | 08 Apr 21 | April 8, 2021 - Josh Groban |
| 137. | 2021-69 | 09 Apr 21 | April 9, 2021 - Bobby Flay |
| 138. | 2021-70 | 12 Apr 21 | April 12, 2021 - Lena Dunham |
| 139. | 2021-71 | 13 Apr 21 | April 13, 2021 - Demi Lovato |
| 140. | 2021-72 | 14 Apr 21 | April 14, 2021 - Kyra Sedgwick |
| 141. | 2021-73 | 15 Apr 21 | April 15, 2021 - Sutton Foster |
| 142. | 2021-74 | 16 Apr 21 | April 16, 2021 - Tom Selleck |
| 143. | 2021-75 | 19 Apr 21 | April 19, 2021 - Terry and Rebecca Crews |
| 144. | 2021-76 | 20 Apr 21 | April 20, 2021 - Jenny McCarthy |
| 145. | 2021-77 | 21 Apr 21 | April 21, 2021 - Willie Geist |
| 146. | 2021-78 | 22 Apr 21 | April 22, 2021 - Neil deGrasse Tyson |
| 147. | 2021-79 | 23 Apr 21 | April 23, 2021 - Kevin Frazier |
| 148. | 2021-80 | 26 Apr 21 | April 26, 2021 - Sarah Chalke |
| 149. | 2021-81 | 27 Apr 21 | April 27, 2021 - Jason Derulo |
| 150. | 2021-82 | 28 Apr 21 | April 28, 2021 - Kevin Bacon |
| 151. | 2021-83 | 29 Apr 21 | April 29, 2021 - Jessica Simpson |
| 152. | 2021-84 | 30 Apr 21 | April 30, 2021 - Oprah Winfrey |
| 153. | 2021-85 | 03 May 21 | May 3, 2021 - Katey Sagal |
| 154. | 2021-86 | 04 May 21 | May 4, 2021 - Catherine Zeta Jones |
| 155. | 2021-87 | 05 May 21 | May 5, 2021 - Laura Prepon |
| 156. | 2021-88 | 06 May 21 | May 6, 2021 - Patricia Heaton |
| 157. | 2021-89 | 07 May 21 | May 7, 2021 - Vanessa Hudgens |
| 158. | 2021-90 | 10 May 21 | May 10, 2021 - David Oyelowo |
| 159. | 2021-91 | 11 May 21 | May 11, 2021 - Courteney Cox |
| 160. | 2021-92 | 12 May 21 | May 12, 2021 - Girls5eva |
| 161. | 2021-93 | 13 May 21 | May 13, 2021 - Julianna Margulies |
| 162. | 2021-94 | 14 May 21 | May 14, 2021 - Adam Sandler |
| 163. | 2021-95 | 17 May 21 | May 17, 2021 - Dylan Farrow |
| 164. | 2021-96 | 18 May 21 | May 18, 2021 - Jason Momoa |
| 165. | 2021-97 | 19 May 21 | May 19, 2021 - Nina Dobrev and Julianne Hough |
| 166. | 2021-98 | 20 May 21 | May 20, 2021 - Hugh Grant |
| 167. | 2021-99 | 21 May 21 | May 21, 2021 - Anne Hathaway |
| 168. | 2021-100 | 24 May 21 | May 24, 2021 - Best of Female Ground Breakers |
| 169. | 2021-101 | 25 May 21 | May 25, 2021 - Best of Lifestyle Segments |
| 170. | 2021-102 | 26 May 21 | May 26, 2021 - Best of Beauty Hour |
| 171. | 2021-103 | 27 May 21 | May 27, 2021 - Best of Co-Stars |
| 172. | 2021-104 | 28 May 21 | May 28, 2021 - Best of Surprises |
| 173. | 2021-105 | 13 Sep 21 | September 13, 2021 - Jennifer Aniston |
| 174. | 2021-106 | 14 Sep 21 | September 14, 2021 - Molly Shannon |
| 175. | 2021-107 | 15 Sep 21 | September 15, 2021 - Cameron Diaz |
| 176. | 2021-108 | 16 Sep 21 | September 16, 2021 - Billie Eilish |
| 177. | 2021-109 | 17 Sep 21 | September 17, 2021 - Cedric the Entertainer |
| 178. | 2021-110 | 20 Sep 21 | September 20, 2021 - Awkwafina |
| 179. | 2021-111 | 21 Sep 21 | September 21, 2021 - Carmelo Anthony |
| 180. | 2021-112 | 22 Sep 21 | September 22, 2021 - John Stamos |
| 181. | 2021-113 | 23 Sep 21 | September 23, 2021 - Martha Stewart |
| 182. | 2021-114 | 24 Sep 21 | September 24, 2021 - Ben Platt |
| 183. | 2021-115 | 27 Sep 21 | September 27, 2021 - Zanna Roberts Rassi |
| 184. | 2021-116 | 28 Sep 21 | September 28, 2021 - Vanessa Hudgens |
| 185. | 2021-117 | 29 Sep 21 | September 29, 2021 - Padma Lakshmi |
| 186. | 2021-118 | 30 Sep 21 | September 30, 2021 - Elmo |
| 187. | 2021-119 | 01 Oct 21 | October 1, 2021 - Phoebe Robinson |
| 188. | 2021-120 | 04 Oct 21 | October 4, 2021 - Bobby Flay |
| 189. | 2021-121 | 05 Oct 21 | October 5, 2021 - 50 Cent |
| 190. | 2021-122 | 06 Oct 21 | October 6, 2021 - Jason Biggs |
| 191. | 2021-123 | 07 Oct 21 | October 7, 2021 - Dakota Johnson |
| 192. | 2021-124 | 08 Oct 21 | October 8, 2021 - The Estefans |
| 193. | 2021-125 | 11 Oct 21 | October 11, 2021 - Adam Lambert |
| 194. | 2021-126 | 12 Oct 21 | October 12, 2021 - Ike Barinholtz |
| 195. | 2021-127 | 13 Oct 21 | October 13, 2021 - Chelsea Handler |
| 196. | 2021-128 | 14 Oct 21 | October 14, 2021 - Meridith Hagner |
| 197. | 2021-129 | 15 Oct 21 | October 15, 2021 - Heather Locklear |
| 198. | 2021-130 | 18 Oct 21 | October 18, 2021 - Scott Speedman |
| 199. | 2021-131 | 19 Oct 21 | October 19, 2021 - Alicia Silverstone |
| 200. | 2021-132 | 20 Oct 21 | October 20, 2021 - Ron Howard |
| 201. | 2021-133 | 21 Oct 21 | October 21, 2021 - Leslie Grossman |
| 202. | 2021-134 | 22 Oct 21 | October 22, 2021 - Gwyneth Paltrow |
| 203. | 2021-135 | 25 Oct 21 | October 25, 2021 - Jaleel White |
| 204. | 2021-136 | 26 Oct 21 | October 26, 2021 - Tom Green |
| 205. | 2021-137 | 27 Oct 21 | October 27, 2021 - Alyssa Milano |
| 206. | 2021-138 | 28 Oct 21 | October 28, 2021 - Rachael Ray |
| 207. | 2021-139 | 29 Oct 21 | October 29, 2021 - Ross Mathews |
| 208. | 2021-140 | 01 Nov 21 | Anderson Cooper |
| 209. | 2021-141 | 02 Nov 21 | Alex Cooper |
| 210. | 2021-142 | 03 Nov 21 | Kristen Bell, Dax Shepard |
| 211. | 2021-143 | 04 Nov 21 | Annaleigh Ashford |
| 212. | 2021-144 | 05 Nov 21 | Billy Porter |
| 213. | 2021-145 | 08 Nov 21 | Michelle Pfeiffer, Katie Sturino |
| 214. | 2021-146 | 09 Nov 21 | Casey Wilson |
| 215. | 2021-147 | 10 Nov 21 | Emily Ratajkowski, Jenny McCarthy |
| 216. | 2021-148 | 11 Nov 21 | Andy Cohen, Zazie Beetz |
| 217. | 2021-149 | 12 Nov 21 | Keke Palmer, Addison Rae |
| 218. | 2021-150 | 15 Nov 21 | America Ferrera |
| 219. | 2021-151 | 16 Nov 21 | Jeff Goldblum |
| 220. | 2021-152 | 17 Nov 21 | Jenny McCarthy |
| 221. | 2021-153 | 18 Nov 21 | Gayle King |
| 222. | 2021-154 | 19 Nov 21 | Bella Twins |
| 223. | 2021-155 | 22 Nov 21 | Charlamagne Tha God |
| 224. | 2021-156 | 23 Nov 21 | Hailee Steinfeld |
| 225. | 2021-157 | 29 Nov 21 | Kathryn Hahn |
| 226. | 2021-158 | 30 Nov 21 | Brooke Shields |
| 227. | 2021-159 | 01 Dec 21 | Dionne Warwick |
| 228. | 2021-160 | 02 Dec 21 | Vanessa Williams |
| 229. | 2021-161 | 03 Dec 21 | Kal Penn |
| 230. | 2021-162 | 06 Dec 21 | Ansel Elgort |
| 231. | 2021-163 | 07 Dec 21 | Whoopi Goldberg |
| 232. | 2021-164 | 08 Dec 21 | Kristin Chenoweth |
| 233. | 2021-165 | 09 Dec 21 | Ariana DeBose |
| 234. | 2021-166 | 10 Dec 21 | Machine Gun Kelly |
| 235. | 2021-167 | 13 Dec 21 | Maya Erskine & Anna Konkle |
| 236. | 2021-168 | 14 Dec 21 | Kristin Davis |
| 237. | 2021-169 | 15 Dec 21 | Jonathan Groff |
| 238. | 2021-170 | 16 Dec 21 | Aubrey Plaza |
| 239. | 2021-171 | 17 Dec 21 | Chelsea Handler |
| 240. | 2021-172 | 20 Dec 21 | Kendrick Sampson |
| 241. | 2021-173 | 21 Dec 21 | Keanu Reeves |
| 242. | 2021-174 | 22 Dec 21 | Reese Witherspoon |
| |
| Season 2022 |
| |
| 243. | 2022-1 | 10 Jan 22 | Courteney Cox |
| 244. | 2022-2 | 11 Jan 22 | Fred Savage |
| 245. | 2022-3 | 12 Jan 22 | Dylan Minnette |
| 246. | 2022-4 | 13 Jan 22 | Jonathan Van Ness |
| 247. | 2022-5 | 14 Jan 22 | Ava Duvernay |
| 248. | 2022-6 | 17 Jan 22 | John Cena |
| 249. | 2022-7 | 18 Jan 22 | Mariska Hargitay |
| 250. | 2022-8 | 19 Jan 22 | Ginnifer Goodwin, Maggie Q, & Eliza Coupe |
| 251. | 2022-9 | 20 Jan 22 | Kyle Mooney |
| 252. | 2022-10 | 21 Jan 22 | Valerie Bertinelli |
| 253. | 2022-11 | 24 Jan 22 | Sarita Choudhury |
| 254. | 2022-12 | 25 Jan 22 | Huma Abedin |
| 255. | 2022-13 | 26 Jan 22 | Cynthia Nixon |
| 256. | 2022-14 | 27 Jan 22 | Kate Hudson |
| 257. | 2022-15 | 28 Jan 22 | Paris Hilton |
| 258. | 2022-16 | 31 Jan 22 | Sheila E |
| 259. | 2022-17 | 01 Feb 22 | Savannah Guthrie |
| 260. | 2022-18 | 02 Feb 22 | 50 Cent |
| 261. | 2022-19 | 03 Feb 22 | Ike Barinholtz |
| 262. | 2022-20 | 04 Feb 22 | Johnny Knoxville |
| 263. | 2022-21 | 07 Feb 22 | Nicole Byer; Chef Edy Massih |
| 264. | 2022-22 | 08 Feb 22 | Sam Richardson |
| 265. | 2022-23 | 10 Feb 22 | Sterling K. Brown; Joey King |
| 266. | 2022-24 | 11 Feb 22 | "I Want You Back" Cast |
| 267. | 2022-25 | 14 Feb 22 | Valentine's Day Show - Gayle King; Taye Diggs |
| 268. | 2022-26 | 15 Feb 22 | Michael Zegen |
| 269. | 2022-27 | 17 Feb 22 | Drew's Crew to the Rescue Hour |
| 270. | 2022-28 | 18 Feb 22 | Drew-Gooder |
| 271. | 2022-29 | 21 Feb 22 | Kat Dennings |
| 272. | 2022-30 | 22 Feb 22 | Drew's Big Birthday Bash! - Rachel Dratch; Ana Gasteyer; The Go-Go's |
| 273. | 2022-31 | 23 Feb 22 | Hannah Waddingham |
| 274. | 2022-32 | 24 Feb 22 | Casey Wilson & Danielle Schneider; Wildflower; Haley Bennett |
| 275. | 2022-33 | 25 Feb 22 | Sophia Bush |
| 276. | 2022-34 | 28 Feb 22 | Joseph Gordon-Levitt; Morena Baccarin |
| 277. | 2022-35 | 01 Mar 22 | Candace Bushnell; Mark Cuban |
| 278. | 2022-36 | 02 Mar 22 | Anna Chlumsky; Aida Rodriguez |
| 279. | 2022-37 | 03 Mar 22 | Drew's News; Eitan Nutella Ravioli |
| 280. | 2022-38 | 04 Mar 22 | Sabrina Carpenter |
| 281. | 2022-39 | 07 Mar 22 | Greg Kinnear |
| 282. | 2022-40 | 09 Feb 22 | Ilana Glazer; Deborah Norville |
| 283. | 2022-41 | 16 Feb 22 | The Colorful Hour |
| 284. | 2022-42 | 08 Mar 22 | Taylor Schilling |
| 285. | 2022-43 | 09 Mar 22 | Sam Heughan |
| 286. | 2022-44 | 10 Mar 22 | Topher Grace; HGTV Stars Mike Jackson & Egypt Sherrod |
| 287. | 2022-45 | 11 Mar 22 | Michelle Buteau |
| 288. | 2022-46 | 14 Mar 22 | Adam Scott |
| 289. | 2022-47 | 15 Mar 22 | Eric Stonestreet |
| 290. | 2022-48 | 16 Mar 22 | Scarlett Johansson |
| 291. | 2022-49 | 17 Mar 22 | Evan Rachel Wood; Debbie Gibson |
| 292. | 2022-50 | 18 Mar 22 | Seth Meyers; Britt Lower |
| 293. | 2022-51 | 21 Mar 22 | Nicola Coughlan |
| 294. | 2022-52 | 22 Mar 22 | Troy Kotsur & Marlee Matli |
| 295. | 2022-53 | 23 Mar 22 | Gabrielle Union, Molly Sims |
| 296. | 2022-54 | 24 Mar 22 | Amy Schumer and Violet Young; Olivia Rodrigo |
| 297. | 2022-55 | 25 Mar 22 | John Cho; Iris Apatow |
| 298. | 2022-56 | 18 Apr 22 | Dee Wallace |
| 299. | 2022-57 | 19 Apr 22 | Claire Foy |
| 300. | 2022-58 | 20 Apr 22 | Mary-Louise Parker |
| 301. | 2022-59 | 21 Apr 22 | Ben Schwartz |
| 302. | 2022-60 | 22 Apr 22 | Neil deGrasse Tyson; Naomie Harris; June Diane Raphael |
| |
